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Non-Profit Public Charity

Managing EPI

Dogs with Exocrine Pancreatic Insufficiency (EPI) have a malabsorption and maldigestion condition where the pancreas is no longer producing enough pancreatic enzymes to digest fats, carbohydrates and proteins. Because of this, dogs (and also cats) will often present with unexplained weight loss, diarrhea/cow-patty like yellow/pale stools. Although EPI was once thought to be just a German Shepherd condition, it is now found in all breeds. That is why Epi4Dogs was created, because of Izzy, a little Spanish Water Dog that wasn’t supposed to have ‘that German Shepherd condition’.

Getting Involved

A treatable condition

Exocrine Pancreatic Insufficiency (EPI) in dogs and cats is when acinar cells atrophy, sometimes called Pancreatic Acinar Atrophy (PAA), in the exocrine part of the pancreas and is no longer producing sufficient digestive enzymes: Lipase, Amylase, Trypsin & Protease that are needed to properly digest nutrients from food. This leads to maldigestion and malabsorption causing weight loss, loose stools, coprophagia, SIBO / SID (small intestinal dysbiosis), low B12. EPI in dogs and cats is manageable with the right balance of pancreatic enzymes with every meal, an agreeable diet, B12 supplementation if needed, along with appropriate SID management with prebiotics, or prebiotics with probiotics, or antibiotics if needed to get SID under control.

Who We Are

Epi4Dogs is a 501(c)(3) Non-Profit Public Charity EPI Research and Awareness organization with zero dollars for administration fees as Epi4Dogs is 100% volunteer-based. Recommendations on this site are supported by EPI veterinarian protocols, veterinarian EPI researchers, veterinarian publications, along with actual EPI pet owner’s day-to-day observations and experience. Epi4Dogs is GDPR Compliant.


Epi4Dogs has and continues to assist and collaborate with various vet schools on EPI genetics, gastrointestinal, and nutritional research to further the understanding of EPI. We have been published multiple times in general media publications and have co-authored veterinarian research publications.

Mission statement

Epi4Dogs Foundation Inc.’s purpose is advancement of science and education of EPI (Exocrine Pancreatic Insufficiency for dogs) by raising funds for EPI research that will yield useful insights or positive outcomes in better managing the EPI health condition in dogs and cats, and promoting EPI education through EPI awareness efforts by educating the public and offering assistance to pet owners, vet schools, veterinarians and veterinary researchers.

A community of volunteers

Our goal is to have the most current EPI information all in one place to better assist the veterinarian community, to help the EPI pet owner readily recognize EPI signs, and to encourage all to work together for the best possible outcome for the EPI dog (and cat)!

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Important introductory information

Here ye, here ye

News & Announcements

Epi4Dogs President's visit with Rilind December 2018

December 26, 2018, our President, Madelon Hale got to visit with Rilind, the famous EPI dog.  Here they are together:

2019 EPI Calendars Availability

The 2019 EPI calendars are READY!!!!

2019 EPI calendars can still be ordered

If you are interested in seeing the 2019 EPI calendars and your pet’s picture was submitted, please go to our EPI Products page  where there is a listing of who’s pet is in which calendar and what month

If you are interested in getting a calendar, on the same EPI Products page, just click on the link for the calendar(s)  you are interested in.  The link will take you directly to the calendar store, where you can view each month of the calendar and make your purchase there too.

If you have any questions about the calendars, please contact Susan at:

  All net donations from these calendars will go in their entirety to our 501c3 public charity organization, The Epi4Dogs Foundation, Inc.  A full accounting of calendar donations will be posted on the Epi4Dogs website. In the past, we have allocated calendar donations in their entirety to EPI Research and EPI Awareness and we will continue to distribute all donations in the same manner.

Zero dollars go to administration fees as Epi4Dogs is a 100% volunteer organization.


Those affected by California Fires in Paradise & surrounding areas


For those devastated in California by the fires in and around Paradise… if you have an EPI pet and are in desperate need for enzymes, please contact Olesia at Epi4Dogs ( with your name, address & pet’s name.

New EPI Dog Research- Aug 22, 2018

EPI Dogs & Lipid Soluble Vitamin Research just published Aug 22, 2018 in the Journal of Veterinary Internal Medicine.  Key investigators Drs. Patrick Barko & David Williams, Univ of Illinois. Epi4Dogs assisted with the patient registry for this study and funding. Epi4Dogs was not involved with the design nor interpretation of any of the findings. The full research can be read on the Epi4Dogs EPI Research page: 

Seminar slides now available

Slide Presentations from the EPI (EXOCRINE PANCREATIC INSUFFICIENCY) SEMINAR on Sept 7, 2017  in Lebanon, TN are on the EPI Seminar page: 

University of Illinois collaboration

In an effort to find possible triggers to EPI, Epi4Dogs is collaborating with the University of Illinois on the Maya Metabolomic Study. Stay posted for updates fall-time of 2018.

EPI is manageable

Before & After

Images of our pups when diagnosed and after proper treatment

Watch this tremendous tribute to the efforts of many members in successfully managing EPI from diagnosis to stability.

This is Rilind, rescued by The Pit Sisters a wonderful organization, who joined our EPI forum and properly diagnosed Rilind with EPI…

…and this is Rilind, 3 months later after proper treatment for EPI was implemented!

Rilind has been adopted to his forever home….. please feel free to follow his story on Rilind Reborn Facebook page!


Chunky Monkey Club!

Success stories from the EPI forum

EPI4dogs on

Had you ever even heard of EPI before having a pet diagnosed? Most of us probably hadn't. Imagine how much faster diagnosis might have been if we had been familiar with it before that. Epi4Dogs Foundation, Inc. has a goal to raise awareness of EPI. Help us do this so the next EPI dog can get diagnosed more quickly. Share this slide with your Facebook friends to help spread the word. Thank you! ... See MoreSee Less

View on Facebook

EPI can be overwhelming when your dog is first diagnosed. We get new people asking questions here on Facebook frequently. What suggestions or advice would you give? Was there one suggestion that really helped you when you first started treatment for your dog? Share your thoughts/suggestions/advice here for all those folks who are still new to EPI! Photos of your healthy EPI dog are also a good way to demonstrate that managing EPI is possible! ... See MoreSee Less

View on Facebook

Our Contacts

Contact Madelon the President or Olesia the Founder of EPI4dogs directly using the details below. Also visit our contact page to send our volunteer staff an email.

 To contact individuals responsible for specific activities please see the Our Team page.



Call our Founder & Research Director, Olesia Kennedy on

(+1) 919-302-9892

Email our  Executive President Madelon Hale at