2023 EPI Research Announcement

Epi4Dogs Foundation Inc.’s mission is the advancement of science and education relating to EPI (Exocrine Pancreatic Insufficiency), yielding useful insights and positive outcomes in better managing EPI in dogs and cats. Our goals are to support and/or collaborate with veterinary EPI research and researchers, and to promote EPI awareness by educating the general public, pet owners, pet organizations, rescue and shelter organizations, veterinary schools and veterinarians.
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Olesia711
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2023 EPI Research Announcement

Post by Olesia711 » 08 Sep 2023, 17:07

After 7 long years of the largest and most detailed EPI Microbiotic and Metabolomic Research study we finally have results of this study.

However... due to the complexity of the study, myself and Dr. Barko worked on summary explanations of the study to better help folks understand how the research was done and how to interpret the results. Below is my summary, but please go to our EPI RESEARCH page to see both Dr. Barko's (and mine is also included) summary explanations and PDF to the actual study results :)
https://epi4dogs.com/epi-research/


Olesia Kennedy
Epi4Dogs Foundation, Inc.
www.epi4dogs.com

Olesia.Kennedy@gmail.com

7 September 2023

New Research Report Has Identified New Metabolic Markers for
Exocrine Pancreatic Insufficiency in Dogs


Epi4Dogs Foundation Inc.’s purpose is to advance science and education of EPI
Exocrine Pancreatic Insufficiency (EPI) in dogs by raising funds for EPI research
that will yield useful insights or positive outcomes to improve the diagnosis and
treatment of the disorder. Epi4Dogs Foundation Inc. has assisted and collaborated with
various veterinary investigators to advance studies of the genetics, gastrointestinal, and
nutritional aspects of EPI.

We are thrilled to announce the results of a recent investigation of metabolism in
dogs with EPI. This research was led by a team of investigators at the University of
Illinois, including Drs. Patrick Barko and David Williams, both board-certified specialists
in small animal internal medicine. This research utilized a cutting-edge method to
measure hundreds of biochemicals involved in metabolic reactions in the blood
of dogs with EPI and compare them to healthy dogs. This approach is called
“untargeted metabolomics” and has the potential to reveal new facets of complex
disorders like EPI. The results of this study have generated novel insights into the
impacts of EPI on metabolism in affected dogs, and has revealed new markers that may
aid in the assessment of its impact on gastrointestinal bacteria and resulting intestinal
dysbiosis.

The study was conducted in collaboration with Epi4Dogs Foundation Inc. and several of
our community members participated in this study by donating samples from their own
dogs. This investigation could not have been possible without the assistance and
participation of the Epi4dogs community. In particular, a generous donation from
Paula and John Gatens was vital to its success.

Untargeted metabolomics investigations are complex, and I have attached to this
announcement a summary of the study provided from the investigators which is
intended to communicate their findings to an audience of non-scientists.

Sincerely,

Olesia Kennedy
Founder, Epi4Dogs Foundation Inc
Olesia, was owned by Izzy, a 35lb Spanish Water Dog (SWD), Diagnosed at 1.5 years old - TLI results 1.. Izzy passed away on February 13, 2020 at 15 years old. She lived with EPI for 13+1/2 years. It was because of Izzy that Epi4Dogs was started... she was the inspiration. May her legacy of helping others with EPI continue for as long as needed.........

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Johnnycake
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Re: 2023 EPI Research Announcement

Post by Johnnycake » 08 Sep 2023, 18:53

This is so cool!!! Thank you for sharing!

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Olesia711
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Posts: 3786
Location: North Carolina
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Pet name: Izzy
My name: olesia

Re: 2023 EPI Research Announcement

Post by Olesia711 » 09 Sep 2023, 11:47

Thank you for reading it.....you are very welcome!
Olesia, was owned by Izzy, a 35lb Spanish Water Dog (SWD), Diagnosed at 1.5 years old - TLI results 1.. Izzy passed away on February 13, 2020 at 15 years old. She lived with EPI for 13+1/2 years. It was because of Izzy that Epi4Dogs was started... she was the inspiration. May her legacy of helping others with EPI continue for as long as needed.........

Barb
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Re: 2023 EPI Research Announcement

Post by Barb » 10 Sep 2023, 18:36

Thank you, Olesia.

Barb

patmize
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Re: 2023 EPI Research Announcement

Post by patmize » 08 Dec 2023, 02:28

Great research about EPI. Thanks for sharing it

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Olesia711
Founder & Research Director
Posts: 3786
Location: North Carolina
Country: United States
State: North Carolina
Pet name: Izzy
My name: olesia

Re: 2023 EPI Research Announcement

Post by Olesia711 » 08 Dec 2023, 14:49

thanks! And we will keep trying until we "hopefully" find more answers!
Olesia, was owned by Izzy, a 35lb Spanish Water Dog (SWD), Diagnosed at 1.5 years old - TLI results 1.. Izzy passed away on February 13, 2020 at 15 years old. She lived with EPI for 13+1/2 years. It was because of Izzy that Epi4Dogs was started... she was the inspiration. May her legacy of helping others with EPI continue for as long as needed.........

cnnsndnsqu
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Re: 2023 EPI Research Announcement

Post by cnnsndnsqu » 11 Dec 2023, 08:25

Barb wrote: 10 Sep 2023, 18:36 Thank you, Olesia.

Barb
I agree with you, the information was helpful

cnnsndnsqu
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Pet name: josh

Re: 2023 EPI Research Announcement

Post by cnnsndnsqu » 12 Dec 2023, 05:50

Olesia711 wrote: 09 Sep 2023, 11:47 Thank you for reading it.....you are very welcome!







Thanks for the information!

DonnaS
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Re: 2023 EPI Research Announcement

Post by DonnaS » 14 Dec 2023, 05:02

cnnsndnsqu wrote: 12 Dec 2023, 05:50
Olesia711 wrote: 09 Sep 2023, 11:47 Thank you for reading it.....you are very welcome!






Welcome to the community!

I agree with you, the information was helpful

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